Tumor Complexity Prompts Caution About Sequencing

More caution about energy and carbon reports.

Caution about Newcastle disease virus-based live attenuated vaccine.

In several recent papers, two published last year in the Journal of Virology by DiNapoli et al. (3) and Ge et al. (4), an earlier study by Martinez-Sobrido et al. in 2006 (6), and a review by Bukreyev et al. in 2006 (1), Newcastle disease virus (NDV) is proposed as a potential vector in the development of a novel bior multivalent vaccine. We question whether those studies satisfactorily address...

Genomic sequencing: The complexity conundrum

The concept of 'organismal complexity' has had a chequered career in genetics, with no rigorous operational definition available for the term. The recent finding that Drosophila melanogaster has more than four thousand fewer genes than the nematode forces a re-examination of whether gene number, in itself, can be taken as any real guide to complexity.

Complexity Results about Nash Equilibria

Noncooperative game theory provides a norma­ tive framework for analyzing strategic interactions. However, for the toolbox to be operational, the so­ lutions it defines will have to be computed. In this paper, we provide a single reduction that 1) demon­ strates -hardness of determining whether Nash equilibria with certain natural properties exist, and 2) demonstrates the -hardness of counting ...

Prompts to increase stair climbing in stations: the effect of message complexity.

BACKGROUND/OBJECTIVE While point-of-choice prompts consistently increase stair climbing, experimental comparisons of message content are rare. Here, the effects of 2 messages differing in complexity about the health outcomes obtainable from stair climbing were compared. METHODS In a UK train station with 2 independent platforms exited by identical 39-step staircases and adjacent escalators, o...